Stopping File From Running

Recently had a case where a file kept running and spawning many instances of itself to keep from being killed.  It was probably Malware (though it called itself Chrome version 36.0.1985.143 with a random exe name Dkzbhjgkyhj.exe). 

Easy way to stop these from running is to just rename the file and extension so that it isn't an executable anymore.  Then you can kill the process in task manager before deleting the file.